Health care is rapidly changing due to innovations in technology, policy and informatics. In 25 years, the needs and type of medical care will look very different than it does today. The future of medicine will have more collaboration, technology, data, and connectedness—and will require a whole new set of skills. To reinvent the future, we need to reinvent Education now for our systems, students and selves. The new accreditation of a Clinical Informatics Fellowship is one means to train future physician leaders; however, there are many other opportunities in undergraduate, graduate, post-doctoral and professional realms to train leaders in medical innovation. We will review new educational opportunities, innovations and best practices that train future leaders and collaborators. Furthermore, education itself is being innovated. We discuss these new educational shifts that change how we teach and learn. Reviewing medical education as a template, we will discuss examples of where innovation is replacing tradition—and can be implemented to better train future physician leaders. Additionally, we will discuss ground-breaking ways engineers and scientists are introduced to the challenges of medicine to help lead better collaborative solutions. Through this presentation: •Get a picture of how telemedicine, simulation, mobile health, innovation, informatics and technology will change how we learn and practice in the next 25 years. •Learn about educational opportunities, innovations and best practices to train future leaders and collaborators. •Walk away with new ideas to train our systems, students and selves to be leaders in the future of health care innovation.